Higher Plasma Concentration of Food-Specific Antibodies in Persons With Autistic Disorder in Comparison to Their Siblings

Specific IgA, IgG, and IgE antibodies to food antigens in 35 participants with autistic disorder and 21 of their siblings in the Republic of Macedonia were examined. Statistically significant higher plasma concentration of IgA antibodies against alpha-lactalbumin, beta-lactoglobulin, casein, and gliadin were found in the children with autistic disorder. Plasma concentrations of IgG antibodies against alpha-lactalbumin, beta-lactoglobulin, and casein in participants with autistic disorder were significantly higher. IgE-specific antibodies (alpha-lactalbumin, beta-lactoglobulin, casein, and gluten), as well as plasma concentration of total IgE, also were statistically significantly higher in the participants with autistic disorder. Gender differences were found for select IgA, IgG, and IgE (but not for total IgE) food-specific antibodies (kU/L) in the participants with autistic disorder and their siblings.

Stress that parents of autistic children and parents of children with cerebral palsy face with

Natasha Mateska1, Vladimir Trajkovski2

1unemployed special educator

2University “Ss. Cyril and Methodius”, Faculty of Philosophy, Institute of Special Education and Rehabilitation, Skopje, Republic of Macedonia

Introduction: Autism is a diagnose that affects every member of the family in different ways. Parents should focus a bigger part of their attention toward the autistic child, which can cause a stressful effect in the family as well as outside the family.

Aim of the study: To determine the stress that parents of autistic children face with compared to parents of children with cerebral palsy.

Methodology: The entire sample includes 90 respondents, of which 45 parents of autistic children and the rest 45 parents of children with cerebral palsy. The survey was conveyed using a questionnaire and methods of descriptive and comparative analysis were used. The comparison of the groups of surveyed was analyzed by using χ2 test and Fisher Exact test. The differences that were taken into consideration were on the level of significance p<0.05.

Results: Parents of autistic children compared with parents of children with cerebral palsy, statistically show significant difference for following variables: support from close community (χ2=7.57, df=1, p=0.006), stigmatization by family and community (χ2=5.4, df=1, p=0.02), isolation by the community (χ2=10.3, df=1, p=0.001), change in the relationship between spouses (χ2=7.53, df=1, p=0.006).

Conclusion: The parents of autistic children are faced with bigger stress in managing the everyday activities and control of life, compared with parents of children with cerebral palsy.

Key words: stress, parents, autism, cerebral palsy

Citation: Mateska N, Trajkovski V. Stress that parents of autistic children and parents of children with cerebral palsy face. Book of abstracts ‡ 9th International Scintific Conference – „Special Education and Rehabilitation Today“. Belgrade, September 25-27, 2015; 31.

Plasma concentration of immunoglobulin classes and subclasses in children with autism in the Republic of Macedonia: retrospective study.